@article{Landman2023,

title = {On Krylov methods for large-scale CBCT reconstruction},

author = {Malena Sabaté Landman and Ander Biguri and Sepideh Hatamikia and Richard Boardman and John Aston and Carola-Bibiane Schönlieb},

doi = {10.1088/1361-6560/acd616},

year  = {2023},

date = {2023-07-01},

journal = {Physics in Medicine &$mathsemicolon$ Biology},

volume = {68},

number = {15},

pages = {155008},

publisher = {IOP Publishing},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Scarth2023,

title = {Manufacture of long spars: Laminate design, experimental trials and non-destructive evaluation},

author = {C. Scarth and Y. Chen and C. Aza and A. T. Rhead and R. Butler},

url = {https://www.sciencedirect.com/science/article/pii/S135983682300149X},

doi = {10.1016/j.compositesb.2023.110646},

issn = {1359-8368},

year  = {2023},

date = {2023-04-01},

journal = {Composites Part B: Engineering},

volume = {255},

pages = {110646},

publisher = {Elsevier BV},

abstract = {Although an enabler of high-rate manufacture, automated forming of components from flat laminates can result in fibre wrinkling. For the first time, fibre length is demonstrated to be a key driver of wrinkling defects when forming a C-spar with a central recess, at industrial length scales. Three such spars, of equal in-plane stiffness, were manufactured using Single Diaphragm Forming. Two contained standard ply angles (0°, 90° or ±45°) including 6 m long 0° fibres but had different stacking sequences, one shown to be formable in short spar trials, the other un-formable. A third spar also had a formable sequence but contained non-standard ply angles (angles other than 0°, 90° or ±45°) so that maximum fibre length was less than 0.6 m. Wrinkles occurred in both standard angle spars but did not occur in the non-standard angle case, demonstrating that use of formable, non-standard angle laminates can reduce scrappage of automatically formed aerospace parts, leading to significant time and cost savings in production.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Danzi2023,

title = {Longitudinal failure mechanisms and crack resistance curves of unidirectional thermoplastic composites},

author = {Federico Danzi and Pedro J. Silva Campos and Albertino Arteiro and Denis Dalli and Carolina Furtado and Jérémy Chevalier and Rodrigo P. Tavares and Frédéric Lani and Pedro P. Camanho},

url = {https://www.sciencedirect.com/science/article/pii/S0013794423001054},

doi = {10.1016/j.engfracmech.2023.109147},

year  = {2023},

date = {2023-04-01},

journal = {Engineering Fracture Mechanics},

volume = {282},

pages = {109147},

publisher = {Elsevier BV},

abstract = {This paper presents a study on the longitudinal fracture toughness, and associated crack resistance curves, of thermoplastic-based composite materials. Double-edge notched (DEN) specimens loaded in tension and compression are used to relate the size-effect laws with the crack resistance curves of unidirectional carbon-fibre reinforced PEKK. The results are corroborated with SEM and fractographic images to provide a better overview of the main failure mechanisms involved during the failure process. Moreover, tensile tests interrupted at 90% of the estimated failure load are CT-scanned to highlight the early stages of the crack propagation. This investigation confirms the suitability of the size-effect method for characterizing thermoplastic composites and it stands out as a first qualitative and quantitative analysis of their characteristic intra-laminar failure mechanisms.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Tolomeo2023,

title = {DEM study of an “avatar” railway ballast with real particle shape, fabric and contact mechanics},

author = {Mathias Tolomeo and Glenn R. McDowell},

url = {https://link.springer.com/article/10.1007/s10035-023-01322-1},

doi = {10.1007/s10035-023-01322-1},

year  = {2023},

date = {2023-03-01},

journal = {Granular Matter},

volume = {25},

number = {2},

publisher = {Springer Science and Business Media LLC},

abstract = {In this paper we show DEM simulations of static and cyclic large triaxial tests on a sample of railway ballast. The sample is reconstructed from X-Ray tomography images of an untested laboratory sample, recovered by impregnation with an epoxy resin. Measurements of both shape and fabric are carried out; the sample shows a high anisotropy of particle orientations due to the preparation procedure and a high shape heterogeneity. A DEM model is then generated using clumps to model single particles, preserving the shape of each particle and the fabric of the sample. Results of static and cyclic simulations are shown and compared with previous simulations on numerically generated samples, showing the importance of an accurate representation of the whole range of particle shapes, as well as confirming the effect of particle anisotropy on the mechanical response.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{CondeGonzalez2023,

title = {Rapid fabrication and screening of tailored functional 3D biomaterials: Validation in bone tissue repair – Part II},

author = {Antonio Conde-González and Michael Glinka and Deepanjalee Dutta and Robert Wallace and Anthony Callanan and Richard O. C. Oreffo and Mark Bradley},

doi = {10.1016/j.bioadv.2022.213250},

year  = {2023},

date = {2023-02-01},

journal = {Biomaterials Advances},

volume = {145},

pages = {213250},

publisher = {Elsevier BV},

abstract = {Regenerative medicine strategies place increasingly sophisticated demands on 3D biomaterials to promote tissue formation at sites where tissue would otherwise not form. Ideally, the discovery/fabrication of the 3D scaffolds needs to be high-throughput and uniform to ensure quick and in-depth analysis in order to pinpoint appropriate chemical and mechanical properties of a biomaterial. Herein we present a versatile technique to screen new potential biocompatible acrylate-based 3D scaffolds with the ultimate aim of application in tissue repair. As part of this process, we identified an acrylate-based 3D porous scaffold that promoted cell proliferation followed by accelerated tissue formation, pre-requisites for tissue repair. Scaffolds were fabricated by a facile freeze-casting and an in-situ photo-polymerization route, embracing a high-throughput synthesis, screening and characterization protocol. The current studies demonstrate the dependence of cellular growth and vascularization on the porosity and intrinsic chemical nature of the scaffolds, with tuneable 3D scaffolds generated with large, interconnected pores suitable for cellular growth applied to skeletal reparation. Our studies showed increased cell proliferation, collagen and ALP expression, while chorioallantoic membrane assays indicated biocompatibility and demonstrated the angiogenic nature of the scaffolds. VEGRF2 expression in vivo observed throughout the 3D scaffolds in the absence of growth factor supplementation demonstrates a potential for angiogenesis. This novel platform provides an innovative approach to 3D scanning of synthetic biomaterials for tissue regeneration.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kyrimis2023,

title = {Towards realistic characterisation of chemical reactors: An in-depth analysis of catalytic particle beds produced by sieving},

author = {Stylianos Kyrimis and Kathryn E. Rankin and Matthew E. Potter and Robert Raja and Lindsay-Marie Armstrong},

url = {https://www.sciencedirect.com/science/article/pii/S0921883122005118},

doi = {https://doi.org/10.1016/j.apt.2022.103932},

year  = {2023},

date = {2023-02-01},

journal = {Advanced Powder Technology},

volume = {34},

number = {2},

pages = {103932},

publisher = {Elsevier BV},

abstract = {Optimization of large-scale fixed particle bed catalytic reactors requires extensive insight into the multi-scale bed structure, even down to the micrometre scale. Theoretical studies of chemical reactors provide a time- and cost-effective means to supporting the optimisation process. However, they rely on simplified assumptions for the particles, e.g. homogeneous perfect spheres. In practise, the preparation of catalytic particles cannot attain this level of uniformity. Typical preparation techniques, such as sieving, are conducted with the aim of obtaining particle size distributions within a pre-defined range, governed by the sizes of the sieves. However, such methods offer limited control in the actual particle sizes and shapes. This paper evaluates the impact of sieving on the resulting particles and overall structural morphology of catalytic beds. The bed structure is quantified using micro-focus computed tomography (µ-CT), enabling the non-destructive examination and analysis of over 150 thousand particles, in terms of particle size, shape, uniformity, and interparticle porosity. Furthermore, the chemical performance of the resulting beds is compared. The detailed characterisation achieved paves the way for the evolution of more rigorous computational models coupling intricate, localised hydrodynamics with realistic chemical processes. Validation of such models at the lab-scale will accelerate the development of more accurate large-scale models.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Clark2023,

title = {3D printed filtration and separation devices with integrated membranes and no post-printing assembly},

author = {Molly Clark and Tushar Garg and Kathryn E Rankin and Darren Bradshaw and Adrian Matthew Nightingale},

url = {https://pubs.rsc.org/en/content/articlepdf/2023/re/d3re00245d},

doi = {10.1039/d3re00245d},

year  = {2023},

date = {2023-01-01},

journal = {Reaction Chemistry &$mathsemicolon$ Engineering},

publisher = {Royal Society of Chemistry (RSC)},

abstract = {Additive manufacturing, or three-dimensional (3D) printing, is an accessible, quick, and user-friendly tool for fabricating reactors and chemical processing devices. Here we report a method for printing filtration and separation devices using fused-deposition modelling (FDM) which incorporate commercial porous membranes. By using exogenous membranes, membrane pore size and material can be arbitrarily specified allowing much greater versatility in device design. We show for the first time that fully operational monolithic devices can be created without need for post-printing assembly and demonstrate the efficacy of the approach by making and testing three distinct devices: dead-end filters, which can be made in a range of sizes and are shown to fully remove micron-sized particles from a heterogenous mixture; liquid–liquid separators, which are shown to completely separate segmented flows of immiscible liquids; and a cross-flow filtration device, which is shown to achieve near full dye removal from an aqueous stream with a residence time of 3.4 minutes. For the cross-flow filtration device we describe a new “double-sided” printing technique whereby the plastic is directly printed onto both sides of the membrane to ensure the membrane is fully bonded to the 3D printed body. The range of devices showcased here highlights the versatility of the approach and its potential for use in chemical processing applications that require porous membranes.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}